Bowhead Research Lab

From Biological Complexity to Clinical Clarity

The modern research lifecycle is a battle against complexity. At Bowhead Research Lab, we help biopharmaceutical teams cut through it—turning fragmented biological data into clear, actionable insight.

Our mission is to accelerate and de-risk therapeutic development by combining biological expertise with computational intelligence. We collaborate with biopharma partners to explore new targets, validate mechanisms, and design more efficient clinical studies.

Guided by Experience

Dr. Francisco Diaz-Mitoma

The Lab is led by Dr. Francisco Diaz-Mitoma, a clinician–scientist with decades of experience translating discovery into licensed vaccines and therapeutics. His leadership spans more than fifty clinical trials and nine approved vaccines, bringing practical insight to every stage of development.

Rooted in Ottawa, Canada

Our Pilot Lab in Ottawa provides a foundation for collaborative discovery and early-stage validation. The facility operates with the support of the National Research Council of Canada and the University of Ottawa, giving partners access to advanced instrumentation, shared research infrastructure, and flexible lab space for joint projects.

Powered by Intelligence

At the core of our work is the Bowhead AI Engine, a clinically validated system that connects molecular, clinical, and real-world data.

Knowledge Graphs

Map relationships between genes, proteins, and delivery pathways.

NLP and LLMs

Extract insight from literature, clinical data, and unstructured notes.

Secure Infrastructure

Ensures compliance with HIPAA, PIPEDA, and GDPR, maintaining full data integrity and ownership.

Every computational output is refined through an expert-in-the-loop process, ensuring predictions are biologically sound and clinically relevant.

Integrated Research & Development Services

Bowhead Research Lab provides a connected suite of services bridging discovery and clinical readiness:

Target Identification and Validation

Multi-omics and literature-driven analysis to identify gene and protein targets with strong translational evidence.

Gene Therapy and Delivery Targeting

Support for payload design, vector optimization, and tissue-specific delivery assessment using in-vitro and organoid systems.

Organoid and Cell-Based Validation

Patient-derived models predicting therapeutic response and resistance with higher fidelity than traditional assays.

Biomarker and Mechanism Studies

Identification and functional validation of biomarkers to guide patient selection and trial design.

Clinical Trial Design and Patient Matching

Data-driven protocol optimization and AI-assisted recruitment through the Bowhead Navigator platform.

Each stage builds on the previous one, creating a continuous feedback loop from computational prediction to biological and clinical validation.

Collaboration Model

We operate as a flexible extension of our partners' R&D teams—offering project-based engagements or full development collaborations. Our focus is on scientific clarity, transparent communication, and measurable progress toward clinical success.

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Every therapeutic challenge is unique.

Connect with our leadership to explore how Bowhead Research Lab—anchored in Ottawa and powered by deep clinical and computational expertise—can help guide your program from discovery to clinical readiness.

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